Alzheimer’s Disease, Dementia and CBD

According to the The World Alzheimer’s Report, nearly 47 million people worldwide are living with Alzheimer’s Disease and/or Dementia. By 2030, this number is set to double. Though Alzheimer’s Disease and Dementia are used interchangeably and Alzheimer’s Disease is considered a form of Dementia, there are notable differences between the two conditions.

What is Dementia?

Dementia is a general term for symptoms that include loss of memory and cognitive decline. Many other issues other than Alzheimer’s can cause Dementia including Huntington’s Disease and Parkinson’s Disease. Though symptoms are very similar to Alzheimer’s Disease, Dementia can be reversible in some cases, particularly when linked with vitamin deficiency, trauma or depression.

What is Alzheimer’s Disease?

Alzheimer’s Disease is a very specific form of Dementia and the most common. The condition is defined by a gradual loss of memory, impaired speech and thinking. According to findings published by The Mayo Clinic, Alzheimer’s Disease is thought to be primarily caused by a combination of lifestyle, genetic and environmental factors. The disease causes brain cells to die off, resulting in the sufferer’s ability to perform daily tasks. Even basic human functions such as swallowing towards the later stages of the illness become extremely difficult and in some cases, impossible. 

Alzheimer’s Disease is named after the German psychiatrist, Dr. Alois Alzheimer. In 1901, Dr. Alzheimer gave the first diagnosis to a 51-year-old patient named Auguste Deter, who exhibited signs of short-term memory loss. Dr. Alzheimer was able to prove that Deter’s symptoms were strongly correlated with the development of amyloid plaques, the abnormal formation of protein clumps between neurons. In addition, Dr. Alzheimer found tangles of a protein called tau which forms part of a structure called a microtubule. This structure is responsible for transporting nutrients from one nerve cell to another.

The basis of Dr. Alois Alzheimer’s research would provide the markers of Alzheimer’s Disease diagnosis, prior to which medical professionals would scan for both amyloid plaques and tau.

Alzheimer’s Disease and a Hollywood Icon

For much of the 20th century Alzheimer’s Disease would continue to be misdiagnosed and largely ignored. It would take Hollywood’s greatest screen icons to bring the disease to the public eye. Legendary movie star, Rita Hayworth, was diagnosed with the disease in 1980. Hayworth’s diagnosis helped bring the disease to the public eye. Along with increased awareness, came much needed public funding towards research. The actress’s diagnosis also led to more screenings for the illness amongst the general populace.

CBD and Alzheimer’s Disease

Over the last 20 years, a number of studies have been conducted on the efficacy of cannabinoid therapy on symptoms related to Alzheimer’s Disease and Dementia.

Tetrahydrocannabinol (THC) has been found to be effective in lowering levels of amyloid-beta peptide, the hallmark characteristic and alleged key contributor to the progression of Alzheimer’s dementia.  The positive mitochondrial function enhancement in animal models suggests that THC could be a potential therapeutic treatment option for Alzheimer’s disease through multiple functions (Cao, et al., 2014).  In turn, the other major cannabinoid, CBD, limits the progression of Alzheimer’s disease by blocking microglial activation and thus providing neuroprotection (Martin-Moreno, et al., 2011) (Ramirez, et al., 2005) and (Campbell & Gowran, 2007). The combination of neuroprotective, anti-oxidative and anti-apoptotic effects provided by CBD decreases the oxidative stress associated with Alzheimer’s disease. (Iuvone, et al., 2004).  The cannabinoid CBC has been shown to encourage neurogenesis (birth of new brain cells), an important process for memory and learning, and to increase the viability of developing brain cells. The decline of growth in these cells is thought to contribute to disorders like Alzheimer’s disease and depression (Shinjyo & Di Marzo, 2013).

Plants Not Pills CBD and Alzheimer’s Disease

Numerous caretakers for sufferers of Alzheimer’s Disease have reported symptom relief in their patients including improved cognitive function and increased appetite. Most popular among all Plants Not Pills products for Alzheimer’s Disease and Dementia has been Revive, Plants Not Pills Full Spectrum CBD Oil with less than 0.3% THC. To learn more about Plants Not Pills CBD, please visit www.plantsnotpillscbd.com, email hello@plantsnotpillscbd.com or call us directly at 888-247-34

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